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This study aimed to explore the capabilities of UV/VIS-based machine vision in tablet inspection as a PAT tool for the determination of compression force and crushing strength, drug content and drug distribution in tablets using meloxicam a yellow model drug.
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WhatsAppGet PriceGet A Quote1. Introduction. In the pharmaceutical industry, assuring that the patient receives a treatment of the specified quality is of utmost importance. This became especially relevant with the release of U.S. Food and Drug Administration (FDA)’s Process Analytical Technology (PAT) initiative (Food and Drug Administration, 2004; Pomerantsev and Rodionova, 2012), as this document encourages
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This work presents a new model based approach to process design and scale-up within the same equipment of a roller compaction process. The prediction of the operating space is not performed fully in-silico, but uses low-throughput experiments as input. This low-throughput data is utilized in an iterative calibration routine to describe the
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